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Vitamin A shows to regulate thyroid hormone metabolism and inhibit thyroid-stimulating hormone (TSH) secretion. A 4-month randomized, double-blind controlled trial of premenopausal women found that Vitamin A caused a significant reduction in serum TSH. The study concluded that vitamin A supplementation might reduce the risk of subclinical hypothyroidism in premenopausal women.
Vitamin A deficiency can also impact thyroid health by playing a role in the pituitary gland, which sends signals (in the form of TSH) to the thyroid to regulate production. A deficiency in vitamin A may limit pituitary synthesis and secretion of TSH, increase the size of the thyroid gland, or reduce uptake of iodine by the thyroid gland.
Vitamin A can also decrease the risk of Hashimoto’s Disease, the autoimmune condition that underlies most cases of hypothyroidism. The vitamin may decrease autoimmune reactions in the body.
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