Your Guide to Thyroid Support Supplements

Safe and effective supplements may help your thyroid symptoms naturally.
Your Guide to Thyroid Support Supplements

Key nutrients drive thyroid hormone production. Nutrient deficiencies can worsen symptoms or prevent thyroid medication from doing its job. Because the thyroid gland is highly nutrient dependent, poor nutritional status is one of the root causes of thyroid dysfunction.

While specific foods and supplements can't treat or reverse thyroid disease, supplements and a thyroid-friendly diet can support your treatment.

So, how to know which supplements can benefit your health? How do you know how much to take? Is more better? How do you know you are getting a quality supplement? Can you cause yourself harm?

The world of supplements is pretty complicated, and many options are more hype than science. It can be tough to decide if you need a supplement and what that supplement should contain.

Supplement Regulation

The Food and Drug Administration (FDA) regulates dietary ingredients and dietary supplements. The FDA's regulation of supplements bases itself on the Dietary Supplement Health and Education Act of 1994 (DSHEA). The definition of a dietary ingredient is a vitamin, minerals, herb, amino acid, or any other substance naturally found in foods that can supplement the diet by increasing intake. Supplement makers cannot make any claims regarding their supplement's ability to "treat, diagnose, prevent or cure any disease."

Under DSHEA, the company manufacturing any dietary supplement takes on the responsibility for ensuring that the product is safe before marketing. The FDA is responsible for monitoring post-market supplement safety. The FDA can remove any supplement that is found to be unsafe—but that may only be after complaints or serious safety issues have been noticed.

Of course, this means that there are products on the market that may be unsafe or ineffective. To ensure that the products you buy are safe and effective, make sure you:

  • Inquire with your healthcare provider to make sure a supplement does not interfere with any medications or therapies you are currently taking.
  • Buy only from reputable and well-established companies. You can find a lot of information about a company through an online search. Quality control and current "Good Manufacturing Practice" (cGMP) may make quality supplements a bit more expensive, and that safety measure is important for your health and well-being!
  • Read the labels—use this chart to determine if you are getting too much (above the Upper Limit (UL)) or the Recommended Daily Allowances (RDAs). Account for any other supplements you are taking.
  • Confirm that a supplement has one of these three seals of approval:
  1. NSF International is an independent non-profit group that certifies supplements and ingredients
  2. The United States Pharmacopeia Convention (USP) is another independent, non-profit organization that analyzes and sets high standards for medicines, food ingredients, and dietary supplements.
  3. Check out supplements with Consumer Labs or LabDoor, another independent testing lab.

Types of Thyroid Support Supplements



The thyroid uses iodine to make the thyroid hormones. The numbers on thyroxine (T4) and triiodothyronine (T3) represent the number of iodine atoms attached to each.

Many years ago, iodine was added to salt (iodized salt) to ensure everyone got enough iodine. However, with so many people reducing their salt intake, now some may need to supplement iodine through diet or supplements. Fish, dairy products, poultry, eggs, kelp, and other seaweeds are excellent sources of iodine.

The RDA for iodine in adults is 150mcg while the UL is 1,100 mcg. Iodine is probably best usually supplied as either potassium iodide (KI), as about 96% of the iodine is absorbed. However, excess iodine may be one cause of hypothyroidism. Consult with your healthcare provider regarding whether you need additional iodine.


Selenium supports thyroid hormone synthesis, and it may reduce the levels of autoantibodies in Hashimoto's thyroiditis. The RDA for selenium in adults is 55 mcg, and the UL is 400 mcg. 

Selenomethionine is usually the form of selenium that is recommended because more than 90% of it can be absorbed. 

Selenium can worsen symptoms of hypothyroidism in those with an iodine deficiency. Consider taking selenium along with iodine, especially if you live in an area with selenium-deficient soil. (Plants take up selenium from the earth.)


Zinc helps with the efficient conversion of T4 to T3. T3 is the active form of thyroid hormone. You need enough zinc to convert T4 to the active T3, and you need enough thyroid hormones around to absorb enough zinc.

The RDA for adults is 11 mg for men, and 9 mg for women. The UL is 40mg for both. Good food sources of zinc include shellfish, meat, nuts, lentils, and other legumes like peas and beans. While the "best" form of zinc is still up for debate, zinc picolinate, gluconate, or acetate rank near the top. 

Many minerals are better absorbed in a chelated (linked) form. These minerals say "chelated" in the description, or have glycinate, picolinate, acetate, citrate, gluconate, or "___ate" in the name. 


Vitamin D

Vitamin D is critically important in many different conditions, including autoimmune responses, heart disease, musculoskeletal health, allergic responses, some forms of cancer, mental health, cognitive functions, and gene regulation.

Adults up to 70 years old should have at least 600 IU (15mcg) daily, while older adults should have at least 800 IU (20mcg) daily. The best sources of Vitamin D are through food (salmon, tuna, mackerel, liver, eggs, and fortified foods) and by moderate sun exposure (15-20 minutes a day on the arms, chest, legs, and face). 

Supplements of D3 are useful to maintain Vitamin D levels, especially during the winter months. D3 is also known as cholecalciferol, not to be confused with D2, ergocalciferol.

B-Complex Vitamins

All the B-complex vitamins can play a role in thyroid disease, and it is usually sufficient to use a quality multivitamin that contains all the B vitamins. Extra Vitamin B12 and folates may improve the response to thyroid hormones and can overall help boost your energy levels.

Myoinositol is a B-vitamin substance that appears to be quite useful in promoting thyroid health in people with Hashimoto's thyroiditis, especially when combined with selenium. The recommended dose is 600 mg myoinositol plus 16.6mg selenomethionine.


When it comes to herbal thyroid support, formulation matters. Traditionally, the delivery of herbs has been with teas or tinctures, often combining a blend of 2-3 herbs. With large concentrations of 2-3 herbs, these traditional delivery systems offer a relatively potent dose.

In more modern times, the potency of herbal supplements has declined significantly. You can buy over-the-counter supplements that contain a blend of 8-10 herbs, possibly in combination with vitamins and minerals, too. While each of the ingredients may act positively on the thyroid, cramming them all into one small capsule, limits their effectiveness. 

Herbs tend to work best as an extract, a mixture that contains hundreds of plant constituents. Modern drugs can be given in small quantities because they are single substances. However, herbs need to be delivered in higher doses and tend to work synergistically with other plant components.

If you want to support your thyroid with herbal supplements, we recommend you:

  • Consult with your healthcare provider. 
  • Choose high-quality herbal supplements.

You should note that herbs have can interact with many different medications. Follow your healthcare provider's advice for safety. Take only the recommended amounts.

Which herbs have the best evidence for supporting thyroid function? Several herbs come from Traditional Chinese Medicine (TCM), Ayurvedic, and Western herbal traditions. These herbs are from a class of botanicals called "adaptogens," which support the thyroid by helping the body respond to stress.


Ashwagandha or Withania somnifera comes from Ayurvedic traditions. Ashwagandha supports the adrenal glands and can reduce high cortisol levels. Ashwagandha should not be used during pregnancy and may worsen autoimmune thyroid disease (and other autoimmune disorders). A recent study indicated that Ashwagandha might boost T4 synthesis and T4-T3 conversion and improve thyroid function in hypothyroid disorders, increasing T3 and T4 levels and decreasing TSH levels. Ashwagandha may be used with thyroid replacement therapy when used cautiously. Please consult your healthcare provider.

Eleutherococcus Seniticosus

Eleutherococcus seniticosus is also known as Siberian ginseng, eleuthero, and Devil's shrub.  Eleuthero is used to moderate the stress response and may help relieve fatigue and anxiety. It may also support energy metabolism, liver function, and can help promote restful sleep.

Centella Asatica

Centella asatica, also known as Gotu kola, comes from Traditional Chinese Medicine (TCM). It may be useful in relieving some of the fatigue and depression often associated with hypothyroidism. Gotu kola should be used cautiously with sedatives.

Schisandra Sinensis

Schisandra sinensis (Schisandra) is another adaptogen used in TCM. The Schisandra berry is used to support the thyroid and liver functions and has anti-inflammatory effects. 

Anti-inflammatory herbs may also be useful for those with Hashimoto's thyroiditis or other autoimmune thyroid disorders. Anti-inflammatory herbs include turmeric, garlic, and ginger. These herbs are good for cooking.


Probiotics are combinations of beneficial bacteria. These bacteria exist in the gut to help digest food, "train" the immune system, maintain a healthy weight, make vitamins, aid in absorption, maintain healthy cholesterol, provide a barrier to infections, and prevent digestive disorders.

Probiotics are in foods like yogurt, kefir, unpasteurized sauerkraut, tempeh, miso, and some cheeses. Sources of prebiotics (food for these beneficial bacteria) include garlic, onions, asparagus, bananas and leeks.

Probiotics are not recommended for critically ill or severely immunocompromised patients, those with short-bowel syndrome or for those who have central venous catheters. Probiotics are recommended for those with autoimmune thyroid disease and support overall health in other forms of hypothyroidism.

Clearly, many nutritional factors play a role in optimizing thyroid function. This information is not intended to diagnose, treat, cure, or prevent any disease. We recommend you work with a Paloma Nutritionist to determine your specific nutritional needs to optimize your thyroid health.

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