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Vitamin E: A Vital Nutrient for Hashimoto’s and Hypothyroidism

Learn about the many benefits of vitamin E for general health and for people with Hashimoto’s and hypothyroidism.
Vitamin E: A Vital Nutrient for Hashimoto’s and Hypothyroidism
Last updated:
10/1/2024
Written by:
Medically Reviewed by:

The Big Picture

Vitamin E is a vital antioxidant that offers numerous health benefits, including protection against oxidative stress, supporting cardiovascular health, and improving immune function. It helps reduce blood pressure, improve cholesterol levels, and lower the risk of blood clots. For thyroid health, particularly in individuals with Hashimoto’s thyroiditis and hypothyroidism, vitamin E is crucial. It may reduce the prevalence of subclinical hypothyroidism and improve thyroid hormone production when paired with nutrients like selenium. Additionally, vitamin E protects thyroid cells from oxidative damage, enhances liver health, and aids in cognitive function for individuals with autoimmune thyroid disease and hypothyroidism.

Vitamin E can be sourced from various foods, making it accessible through a balanced diet. Nuts and seeds, particularly almonds and sunflower seeds, are rich sources. Vegetable oils like wheat germ, sunflower, and safflower also provide substantial amounts. Additionally, avocados, red bell peppers, spinach, broccoli, and fatty fish like salmon and trout offer vitamin E. For those unable to meet their needs through diet alone, vitamin E supplements, particularly natural forms like d-alpha-tocopherol, are available. However, it’s essential to consult a healthcare provider to determine the correct dosage, as excessive intake can interfere with thyroid hormone production.

In this article

Vitamin E is a powerful antioxidant crucial in maintaining overall health and well-being. This fat-soluble vitamin is found naturally in various foods and is available as a dietary supplement. Vitamin E offers a wide range of health benefits, and recent research has also reported on specific benefits of vitamin E for patients with Hashimoto’s thyroiditis and hypothyroidism. In this article, we’ll explore the role of vitamin E in overall health, and specifically for your thyroid health.

Health benefits of vitamin E

Let’s look at the many potential health benefits of vitamin E.

- Antioxidant properties

One of vitamin E’s primary functions is its potent antioxidant activity. It helps protect cells from oxidative stress by neutralizing harmful molecules called free radicals. This protective antioxidant effect is particularly important for maintaining cellular health and potentially reducing the risk of chronic diseases associated with oxidative damage.

- Cardiovascular health

Vitamin E may contribute to heart health in several ways:

  • Blood pressure regulation: Some studies suggest that vitamin E supplementation can help reduce systolic blood pressure, the top number in a blood pressure reading.
  • Lipid profile improvement: When combined with omega-3 supplements, vitamin E may help lower LDL (bad) cholesterol and triglyceride levels.
  • Thromboembolism risk reduction: Research indicates that vitamin E supplements may decrease the risk of mortality from thromboembolism by reducing the tendency for blood clotting.

- Skin health

The antioxidant properties of vitamin E may benefit skin health. While more research is needed, some studies suggest that vitamin E supplements could be helpful for certain skin conditions, such as eczema.

- Cognitive function

Maintaining optimal vitamin E levels may help protect against cognitive decline. However, the effects of vitamin E supplements on cognitive conditions like Alzheimer’s disease are still unclear and require further research.

- Immune system support

Vitamin E plays a crucial role in supporting the immune system. It helps strengthen the body’s natural defense against viruses and bacteria. This immune-boosting effect is particularly important for maintaining overall health and preventing infections.

- Red blood cell formation

Vitamin E contributes to the formation of red blood cells and helps widen blood vessels, preventing blood from clotting within them. This function is essential for maintaining healthy circulation and oxygen delivery throughout the body.

- Cellular communication

At a cellular level, vitamin E facilitates communication between cells, enabling them to carry out many essential functions. This role in cellular signaling is crucial for various physiological processes in the body.

- Potential cancer prevention

While more research is needed, some studies suggest that vitamin E may have a role in cancer prevention. Observational studies have shown an inverse relationship between dietary vitamin E intake and the risk of certain cancers, including kidney and bladder cancer. However, it’s important to note that randomized controlled trials are still needed to confirm these potential benefits.

- Eye health

Vitamin E, along with other antioxidants, may help protect the eyes from free radical damage. This could potentially reduce the risk of age-related eye conditions, although more research is needed to understand this relationship fully.

Vitamin E and its benefits for Hashimoto’s and hypothyroid patients

Vitamin E is crucial in supporting thyroid health, particularly for individuals with autoimmune thyroid disease and hypothyroidism. This powerful antioxidant offers several specific benefits that can help manage these conditions and improve overall thyroid function.

- Reduced rates of subclinical hypothyroidism and Hashimoto’s thyroiditis

Vitamin E intake is associated with a lower prevalence of subclinical hypothyroidism and autoimmune Hashimoto’s thyroiditis among men, according to study results published in Thyroid. The researchers concluded that a higher level of vitamin E intake appears to have a protective effect against the development and progression of Hashimoto’s hypothyroidism.

- Improved thyroid function

Supplementing with vitamin E may help enhance thyroid function in people with Hashimoto’s disease. When combined with other nutrients like selenium, vitamin E can support optimal thyroid hormone levels.

Research has shown that vitamin E deficiency can impair the body’s ability to produce thyroid-stimulating hormone (TSH) while simultaneously increasing the production of T3 and T4 hormones. This imbalance can contribute to thyroid dysfunction.

- Thyroid hormone conversion and synergy with selenium

Vitamin E works synergistically with selenium, another crucial nutrient for thyroid health, to support the conversion of T4 (the inactive form of thyroid hormone) to T3 (the active form). By ensuring adequate vitamin E intake, people with hypothyroidism may help support proper thyroid hormone conversion, which is critical for proper thyroid function and is often impaired in individuals with hypothyroidism.

Additionally, combining vitamin E and selenium helps protect thyroid cells from oxidative damage caused by excess iodine processing. This is particularly important for individuals with Hashimoto’s, who may be more sensitive to iodine fluctuations.

- Liver health

Vitamin E shows promise in supporting liver health, particularly for individuals with non-alcoholic fatty liver disease (NAFLD). People with Hashimoto’s and hypothyroidism have an increased risk of NAFLD. Studies have found that vitamin E supplementation can reduce levels of liver enzymes, decrease blood lipid levels, and improve overall liver health in NAFLD patients.

- Cellular support

Research has shown that vitamin E has a direct cellular effect on the thyroid gland, as well as the adrenal and pituitary glands. Studies on vitamin E-deprived rats revealed underdeveloped thyroid glands, highlighting the importance of this nutrient for thyroid health.

- Reduced inflammation

The anti-inflammatory properties of vitamin E can help mitigate the chronic inflammation associated with Hashimoto’s thyroiditis. By reducing inflammation, vitamin E may help slow the autoimmune attack on the thyroid gland.

- Enhanced cognitive function

Many individuals with hypothyroidism experience cognitive issues, often referred to as “brain fog.” A study found that combining vitamin E supplementation with levothyroxine (a common thyroid hormone replacement medication) may help prevent oxidative stress and cognitive problems in hypothyroid patients.

- Cardiovascular protection

People with hypothyroidism have an increased risk of cardiovascular disease. Vitamin E’s antioxidant properties may offer additional protection for heart health in thyroid patients. A study on hypothyroid rats found that vitamin E supplementation, along with levothyroxine replacement therapy, improved myocardial health by reducing oxidative stress and improving thyroid function.

- Antioxidant protection

One of the primary beneficial effects of vitamin E for thyroid health is its potent antioxidant properties. In Hashimoto’s thyroiditis, an autoimmune condition, the thyroid gland is subject to oxidative stress and inflammation due to the ongoing attack by thyroid antibodies. Vitamin E helps combat this by neutralizing free radicals and reducing oxidative damage to thyroid cells.

- Immune system support

Vitamin E plays a vital role in supporting overall immune function. This immune-modulating effect may be particularly beneficial for individuals with Hashimoto’s thyroiditis, an autoimmune condition. By supporting a healthy immune response, vitamin E may help modulate immune function and reduce the autoimmune attack on the thyroid gland.

Best food sources of vitamin E

Incorporating vitamin E-rich foods into your diet is the most natural and effective way to meet your daily requirements. Here are some of the best sources:

- Nuts and seeds

Almonds are high in vitamin E, providing about 7.3 mg per ounce (about 23 nuts). Sunflower seeds are another excellent source, offering 7.4 mg per ounce. Other vitamin E-rich nuts and seeds include hazelnuts, peanuts, and pine nuts.

- Vegetable oils

Wheat germ oil is the richest natural source of vitamin E, containing a whopping 20 mg per tablespoon (135% of the daily value). Other oils high in vitamin E include sunflower, safflower, and hazelnut oils.

- Fruits and vegetables

While not as concentrated as nuts and oils, specific fruits and vegetables provide significant amounts of vitamin E. Avocados, for instance, contain about 2.1 mg in half a fruit. Red bell peppers, spinach, and broccoli are also good vegetable sources.

- Fish

Some fish, particularly fatty fish, are good sources of vitamin E. Atlantic salmon and rainbow trout provide about 2 mg per fillet.

It’s not always easy to get the RDA of vitamin E from food sources. This is where supplements come in.

When selecting a vitamin E supplement, consider the following factors:

Best form of vitamin E

Vitamin E supplements come in two main forms: natural vitamin E, labeled as “d-alpha-tocopherol” or “mixed tocopherols,” and synthetic vitamin E, labeled as “dl-alpha-tocopherol.” Choose natural vitamin E, as it is generally considered more potent and better absorbed by the body than synthetic forms. Also, look for products containing the full spectrum of vitamin E compounds, including tocopherols and tocotrienols. Many supplements on the market only contain alpha-tocopherol, which doesn’t provide the full range of benefits.

Dosage of vitamin E

While vitamin E offers numerous benefits for thyroid health, it’s essential to approach supplementation carefully. The recommended dietary allowance (RDA) for vitamin E is 15 mg (22.4 IU) daily for adults. (For breastfeeding women, the RDA is 19 mg/day.)

However, some studies have used higher doses for therapeutic effects.

As noted, the recommended daily allowance (RDA) for vitamin E is 15 mg for adults. However, therapeutic doses for thyroid health may be higher. Always consult a healthcare provider to determine the appropriate dosage for your needs.

Quality and purity

Look for supplements that have been third-party tested for purity and potency.

Delivery method

Vitamin E supplements come in various forms, including soft gels, capsules, and liquid. Choose the form that’s most convenient for you.

Synergistic nutrients

Vitamin E works best when combined with other nutrients that support thyroid health. Consider incorporating the following:

Selenium: Selenium supplements work synergistically with vitamin E to support thyroid hormone conversion.

Zinc: Zinc is essential for thyroid hormone production.

Vitamin D: People with Hashimoto’s are often deficient in Vitamin D, crucial for immune system regulation.

B vitamins: Support overall thyroid function and energy production.

Cautions

High-dose vitamin E supplements can potentially interfere with blood clotting and interact with certain medications, so it’s essential to consult a healthcare professional who can recommend the most appropriate type and dosage based on your health status and needs.

It’s important to note that vitamin E supplements often contain soy lecithin, which can be problematic for people with Hashimoto’s who may have soy sensitivities. Look for soy-free options, such as those derived from sunflower seed oil.

Also, excessive vitamin E intake (more than 1,000 mg or 1,500 IU per day) can have adverse effects. Specifically, it may potentially interfere with thyroid hormone production. Therefore, it’s best to consult a healthcare provider before starting any supplementation regimen.

Optimal dosing of vitamin E supplements

Optimal dosing of vitamin E supplements

While vitamin E offers numerous benefits for thyroid health, it’s essential to approach supplementation carefully. The recommended dietary allowance (RDA) for vitamin E is 15 mg (22.4 IU) daily for adults. (For breastfeeding women, the RDA is 19 mg/day.)

However, some studies have used higher doses for therapeutic effects.

As noted, the recommended daily allowance (RDA) for vitamin E is 15 mg for adults. However, therapeutic doses for thyroid health may be higher. Always consult a healthcare provider to determine the appropriate dosage for your needs.

A note from Paloma

While vitamin E is not a cure-all for Hashimoto’s and hypothyroid patients, the potential benefits of this vital nutrient for general health and thyroid function make it a valuable addition to a comprehensive thyroid health strategy. As research continues, we may uncover even more ways this essential vitamin contributes to our thyroid health.

While it’s generally best to obtain vitamins through a balanced diet, supplementation may be beneficial in some instances under the guidance of a healthcare professional. A knowledgeable practitioner can help you assess your vitamin E levels, recommend appropriate dosages, and monitor your progress over time.

Paloma Health offers its members comprehensive support for managing Hashimoto’s and hypothyroidism through a holistic approach that includes nutritional coaching and expert medical guidance.

Paloma members can work with experienced nutritionists on your care team to focus on your thyroid health. These experts can provide personalized dietary and supplement recommendations tailored to each individual’s needs, helping to reduce inflammation and alleviate symptoms associated with thyroid conditions.

Paloma Health also connects members with top thyroid specialists who can offer personalized treatment plans. These doctors are well-versed in the latest research and can guide supplement choices, including vitamin E, which may benefit some patients with thyroid disorders.

The Paloma Health app allows members to easily schedule video consultations with their healthcare providers, access educational resources, and even order at-home thyroid testing kits. This seamless integration of services ensures that members have all the tools they need to manage their thyroid health effectively.

When you’re a Paloma member, you can proactively approach your thyroid care, working closely with experts to develop a comprehensive treatment plan that addresses all aspects of your health and well-being.

References:

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MedlinePlus. Vitamin E: MedlinePlus Medical Encyclopedia. Medlineplus.gov. Published 2019. https://medlineplus.gov/ency/article/002406.htm

Liu S, Lu C, He L, Shan Z, Teng W, Li Y, Liu T. Vitamin E Intake and Prevalence Rates of Thyroid Dysfunction and Autoimmune Thyroiditis: A Cross-Sectional Analysis of NHANES Data. Thyroid. 2024 Jun;34(6):753-763. doi: 10.1089/thy.2023.0561. Epub 2024 Apr 8. PMID: 38534308. https://pubmed.ncbi.nlm.nih.gov/38534308/

Thi My, L. Can thyroid tumors take vitamin E? Vinmec Hospital. https://www.vinmec.com/eng/article/can-thyroid-tumors-take-vitamin-e-en

Tousson E, Ali EMM, Ibrahim W, Mansour MA. Levothyroxine replacement therapy with vitamin E supplementation prevents oxidative stress and cognitive deficit in experimental hypothyroidism. Endocrine. 2012;43(2):434-43 https://link.springer.com/article/10.1007/s12020-012-9801-1

Vitamin E. The Nutrition Source. Harvard T.H. Chan School of Public Health. May 23, 2024. https://nutritionsource.hsph.harvard.edu/vitamin-e/

National Institutes of Health. Office of Dietary Supplements - Vitamin E. Nih.gov. Published March 26, 2021. https://ods.od.nih.gov/factsheets/VitaminE-HealthProfessional/

DellaPenna D, Laurent Mène-Saffrané. Vitamin E. Advances in botanical research. Published online January 1, 2011:179-227. doi:https://doi.org/10.1016/b978-0-12-385853-5.00002-7 https://www.sciencedirect.com/science/article/abs/pii/B9780123858535000027

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Mary Shomon

Patient Advocate

Mary Shomon is an internationally-recognized writer, award-winning patient advocate, health coach, and activist, and the New York Times bestselling author of 15 books on health and wellness, including the Thyroid Diet Revolution and Living Well With Hypothyroidism. On social media, Mary empowers and informs a community of more than a quarter million patients who have thyroid and hormonal health challenges.

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